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Characterization of progesterone loaded biodegradable blend polymeric nanoparticles Ciência Rural
Leimann,Fernanda Vitória; Biz,Maiara Heloisa; Kaufmann,Karine Cristine; Maia,Wallace José; Honçalves,Odinei Hess; Cardozo Filho,Lucio; Sayer,Claudia; Araújo,Pedro Henrique Hermes de.
ABSTRACT: The encapsulation of progesterone in poly (hydroxybutirate-co-hydroxyvalerate) (PHBV), poly (ε-caprolactone) (PCL), poly (L-lactic acid) (PLLA) nanoparticles and PHBV/PCL and PHBV/PLLA blend nanoparticles was investigated in this research. Nanoparticles were produced by miniemulsion/solvent evaporation technique with lecithin as surfactant and were characterized regarding to z-average diameter (Dz) and polydispersity (PDI), progesterone recovery yield and encapsulation efficiency. Possible interactions between progesterone and the polymer matrices were investigated by Fourier Transform Infrared Spectroscopy (FTIR). High recoveries (up to 102.43±1.80% for the PHBV/PLLA blend) and encapsulation efficiencies (up to 99.53±0.04% for PCL) were achieved...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Progesterone; Drug-polymer interactions; PHBV; PLLA; PCL.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782015001102082
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Effect of recycling on mechanical behaviour of biocompostable flax/poly(L-lactide) composites ArchiMer
Le Duigou, Antoine; Pillin, Isabelle; Bourmaud, Alain; Davies, Peter; Baley, Christophe.
The biocompostability of natural fibre-reinforced biopolymers, also known as biocomposites, makes them an attractive alternative to glass fibre-reinforced petrochemical polymers. The aim of this work is to study the capacity of flax/PLLA (poly(L-lactide)) biocomposite (20% and 30% fibres by weight) to be recycled. Mechanical properties were evaluated initially, and shown to be similar to those of glass/PP and superior to hemp/PP and sisal/PP composites. Then after repeated injection cycles tensile properties were shown to be conserved until the third cycle. Matrix degradation and fibre aspect ratio were followed using molecular weight measurements, thermal and rheological analyses, image analysis of sections and SEM fractography. These techniques revealed...
Tipo: Text Palavras-chave: Mechanical properties; Recycling; Flax fibres; PLLA.
Ano: 2008 URL: http://archimer.ifremer.fr/doc/2008/publication-6360.pdf
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